Abstract:

Recently, hyperthermia has been employed clinically as one of a variety of multimodal therapies for cancer. Hyperthermia has been applied locally, regionally, and systemically to various tumors. Local or regional hyperthermia has the advantage that a localized tumor can be heated to temperatures higher th an 420C, the maximum for total-body hyper ther mia.V There is mounting evidence to support a hypothesis that cancer cells are more selectively sensitive to heat than are normal cells, due to the poor blood supply ofneoplastic tissue and the decreased vasodilatation capacity of the neovascular bed.

Authors:

Emma J. Patterson, B.Sc.(Hon), M.D., Charles H. Scudamore, M.D., F.A.C.S., F.R.C.S.(C, Ed, Eng), Andrzej K. Buczkowski, M.D., David A. Owen, M.B., F.R.C.P.ath, F.R.C.P.C., Alex G. Nagy, M.D., F.R.C.S.C.

For Direct IP Access please click this link