Experimental Spinal Cord Repair (By Means of Direct Connection of the Above-the-Lesion CNS with PNS)

Abstract:

There are no medical or surgical treatments able to repair traumatic paraplegia. Experiments done by connecting the above-the-lesion with the below-the-lesion cord by means of PNS grafts have always failed. The grafts are reinhabited by regrowing axons of the first motoneurons which however are not able to progress into the distal spinal cord. At the present state of knowledge no surgical treatment can cure paraplegia. Thousands of researchers are working all over the world in many different types of research ranging from molecular biology to embriology, and from biochemistry to pharmacology and surgery. None of these experiments have proved to be practically effective.

Authors:

Giorgio A. Brunelli, M.D., Giovanni R. Brunelli, M.D.

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