Abstract:

A61-year-old postmenopausal woman with ovarian carcinoma was treated with two surgical operations and a series of platinum-based chemotherapy. A solitary metastasis into the splenic parenchyma was identified 33 months after the second surgery by abdominal computed tomography with an increased serum level of CA-125. She underwent a pancreaticosplenectomy and received platinum-based adjuvant chemotherapy continuously for 2 years. Her serum CA-125 level decreased to a normal range and she has lived without any recurrence for more than 10 years after the splenectomy. Solitary metastases from ovarian cancer into the splenic parenchyma are extremely rare. Among 18 cases previously reported, this present case shows the longest disease-free survival. Because these cases show favorable prognosis after splenectomy, surgical treatment should be considered along with adjuvant chemotherapy.

Authors:

Ryuji Yoshioka, M.D., Chief Resident, Department of Surgery, Takehiro Okabayashi, M.D., Assistant Professor, Department of Surgery, Isao Nishimori, M.D., Assistant Professor, Department of Gastroenterology and Hepatology, Nagamasa Maeda, M.D., Associate Professor, Department of Gynecology, Takeki Sugimoto, M.D., Associate Professor, Department of Surgery, Takuhiro Kohsaki, M.D., Assistant Professor, Department of Gastroenterology and Hepatology, Saburo Onishi, M.D., Professor, Department of Gastroenterology and Hepatology, Takao Fukaya, M.D., Professor, Department of Gynecology, Michiya Kobayashi, M.D., Professor, Department of Clinical Health and Medical Services, Kazuhiro, Hanazaki, M.D., Professor, Department of Surgery, Kochi Medical School, Nankoku, Kochi, Japan

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