Integra

Abstract:

Integra® Bilayer Wound Matrix is composed of cross-linked bovine tendon collagen and glycosaminoglycan with a semi-permeable polysiloxane membrane. This bioengineered tissue provides a matrix for organized cellular migration and proliferation needed to facilitate wound healing while minimizing an inflammatory response. The scaffold provided by Integra® Bilayer Wound Matrix is particularly helpful for building a durable base for coverage of deep soft tissue defects in wounds of all types. We consider the current literature on Integra® Bilayer Wound Matrix and discuss the peri-application management, as well as introduce our treatment algorithms for its use in complex soft tissue reconstruction in the lower extremity.

Authors:

Paul J. Kim, DPM, MS, Associate Professor, Center for Wound Healing & Hyperbaric Medicine, Department of Plastic Surgery, Georgetown University Hospital, Washington, District of Columbia, Christopher E. Attinger, MD, Professor, Division Chief, Center for Wound Healing & Hyperbaric Medicine, Department of Plastic Surgery, Georgetown University Hospital, Washington, District of Columbia, John S. Steinberg, DPM, Associate Professor, Center for Wound Healing & Hyperbaric Medicine, Department of Plastic Surgery, Georgetown University Hospital, Washington, District of Columbia, Karen K. Evans, MD, Assistant Professor, Center for Wound Healing & Hyperbaric Medicine, Department of Plastic Surgery, Georgetown University Hospital, Washington, District of Columbia

PMID:  24504739

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