Abstract:

Management of severe surgical infections remains difficult and requires a multifaceted approach. In this review, we briefly summarise our approach to surgical infection, concentrating on the underlying pathological processes of intraabdominal infection. Two promising new therapies–activated protein C (ACP) and stress-dose hydrocortisone–are reviewed as adjunctive management in treatment of patients with septic shock.

Authors:

Ian D. Mcgilvray, M.D., Ph.D., F.R.C.S.C., Ori D. Rotstein, M.D., F.R.C.S.C

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