Abstract:

In the past three decades, the prevalence of aortic aneurysms has increased threefold. Incidence of aortic aneurysms increases with age and as the population ages, the prevalence increases. Population-based studies have shown that 10% of men over the age of 70 have abdominal aortic aneurysms. After many years of research, the exact pathogenesis of degenerative aneurysms -the most common form of aneurysm- is still unknown, although a number of factors including genetic, protelytic enzymes, hemodynamics, inflammation, and infection have been implicated.

Authors:

Christopher K. Zarins. M.D., F.A.C.S., Stanford University School of Medicine, Stanford, CA; Ramin E. Beygui, M.D., Stanford University Medical Center, Stanford, CA

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